Targeted therapies are the state of the art in oncology today, and every year new Tumor-associated antigens (TAAs) are developed for preclinical research and clinical trials, but few of them really change the therapeutic scenario.Difficulties, either to find antigens that are solely expressed in tumors or the generation of good binders to these ant
The evolutionarily conserved target of rapamycin complex 1 (TORC1) controls growth-related processes such as rockfleece protein, nucleotide, and lipid metabolism in response to growth hormones, energy/ATP levels, and amino acids.Its deregulation is associated with cancer, type 2 diabetes, and obesity.Among other substrates, mammalian TORC1 directly
Abstract Background 49ers gold hex code Animal mycobacterioses are regarded as a potential zoonotic risk and cause economical losses world wide.M.avium subsp.hominissuis is a slow-growing subspecies found in mycobacterial infected humans and pigs and therefore rapid and discriminatory typing methods are needed for epidemiological studies.The geneti